Synthes and bioresorbable internal fixation devices

Growing prevalence of myopia, growing geriatric population, and increasing preference for contact lenses over prescription eyeglasses are the major factors driving the growth of this market. On the other hand, shortage of trained ophthalmologists and regulatory barriers in the contact lenses market are some of the factors restraining market growth.

At the first visit on the six day after onset, the X - ray was normal. On the same day, MRI findings was osteomyelitis in the middle phalanx.

However, the serum inflammatory response was negative. Serum rheumatic response was also negative, but antinuclear antibody was positive at times. On the 12th day after onset of disease, the vicinity of the epiphyseal line of the middle phalanx became erosive. At this point, from literature search and pediatric consultation, we got a diagnosis of Microgeodic disease.

The antibiotic was discontinued. Pain was relieved 2. At 4 weeks after onset, the middle phalanx fractured and fixed with the splint. Bone fusion was somewhat late. There was no deformation healing, but the epiphyseal line of middle phalanx and distal phalanx closed. At 7 months after onset, the difference in bone length between bilateral middle phalanges was 2 mm.

The finger healed without dysfunction. Redness and swelling of fingers and toes like frostbite.

It is accompanied by mild pain and itching. Predilection age is elementary school age 6 - 12 years old. It is mainly in the middle phalanx.

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A bone resorption image is recognized in the X-ray image. The cause is unknown, it is thought to be a transient bone circulation disorder. Prognosis is usually good, it will heal spontaneously in about 6 months. In this case, owing to attaching a diagnosis at a relatively early stage, appropriate treatment could be done.

Microgeodic disease was reported 24 papers in PubMed. Since the arterial arch of the hand is predominant on the ulnar side, it seems that this disease is many in the index finger. Oberg-Manske-Tonkin [OMT]-classificationbut none of these describe involvement proximal from the wrist other than radio-ulnar synostosis.

One case of longitudinal cleavage of the upper extremity has been described in the literature. Materials and methods An otherwise healthy 8-month-old infant presented with congenital split right forearm.

Results Starting from the elbow joint, the forearm is divided into a superior radial forearm with a thumb and an index finger and an inferior ulnar forearm with two fingers.

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X-rays showed a radius and two metacarpals in the radial forearm and a hypoplastic ulna and a single metacarpal supporting two digits in the shorter ulnar forearm. The elbow joint of the radial part had an active and passive extension lag of 60 and 50 degrees, respectively, and an active and passive flexion of and degrees, respectively.

An ulnohumeral synostosis was present and the ulnar forearm showed no motion.Internal fixation devices in the past had been made of stainless steel or titanium, but with problems resulting from those permanent devices, an innovative approach is being considered. Bioresorbable implants are a possible replacement to.

Nicola Fava's Viewpoint: Managing Technology: Synthes' Case

Internal fixation devices in the past had been made of stainless steel or titanium, but with problems resulting from those permanent devices, an innovative approach is being considered.

Bioresorbable implants are a possible replacement to. BADM Chuan Huang (Group 1) Synthes First and Second Mover Synthes was the leading manufacturer and distributor of “internal fixation devices” used by trauma surgeons in , with a US market share of approximate 50%%(1).

CASE ANALYSIS Synthes 1. Situation Analysis: A. Nature of Demand The products in discussion are ‘bioresorbable’ internal fixation devices. These devices are surgically placed to stabilize broken bones, aiding in allowing the body to heal itself. Managing Technology: Synthes' Case Introduction Synthes is a leader maker and distributor of “internal fixation devices” and has to make a choice about a new technology (Bioresorbable implants).

The main options available for the company are: 1. Synthes management asked a Harvard Business Team review board to evaluate the potential for moving forward with bioresorbable internal fixation devices.

The purpose of this case was to see how feasible and beneficial it would be for Synthes to enter the bioresorbables market.